Drug Analysis
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With the advent of newer drug molecules either partially synthesized, totally synthesized or isolated from naturally occurring microbial and plant products—it has become absolutely necessary to ascertain and examine critically their physical characteristics, chemical equivalence, chemical impurities and their prescribed limits, degradation of products, metabolites and above all their biological features. The dosage forms having either single or multi-component formulated product. The fundamental reasons for this sudden legitimate is to ‘analysis of drug substances’ are perhaps due to the tremendous growth in the progress of ‘medicinal chemistry’ towards achieving one ultimate objective which is to obtain ‘better drugs for a better world.
Forensic labs are often called in to identify unknown powders, liquids and pills that may be illicit drugs. There are basically two categories of forensic tests used to analyse drugs and other unknown substances: Presumptive tests (such as colour tests) give only an indication of which type of substance is present -- but they can't specifically identify the substance. Confirmatory tests (such as gas chromatography/mass spectrometry) are more specific and can determine the precise identity of the substance.
- Sample preparation
- Extraction techniques
- Extraction from solid samples
- Extraction from liquid samples
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