Drug Metabolism Studies
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Metabolism was previously known as ‘detoxication’ mechanism in the body. It is the mechanism of elimination of foreign and undesirable compounds from the body and control the level of desirable compounds such as vitamins in the body. Metabolism of the drug plays significant role in selection and characterisation of drugs. The major site of metabolism in the body is Liver.
- Synthetic porfirines
- The Fenton-reaction
- Electrochemical oxidation
- In vitro and ex vivo techniques
- Immobilized enzyme reactors (IMER)
- Liver cell lines
- Liver slices, isolated perfused liver
- Integrated discrete multiple organ co-culture system (IdMOC)
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