 Innovative Therapies for Serious Diseases
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Innovative Therapies includes correcting a defective gene, inserting a gene-drug, grafting cells capable of regenerating healthy tissue. In patients with rare, severe immune-mediated inflammatory diseases (IMIDs), biologics are often the last treatment option when standard therapy with classical immunosuppressive drugs fails. However, clear guidelines on biologic prescription in these diseases are often lacking. A major reason is that proper randomized controlled trials (RCTs) are difficult to design due to the low prevalence, heterogeneity of patients, and the severe medical condition of patients. Since RCTs are usually required for registration of therapy for a specific disease, physicians often prescribe biologics off-label in these diseases. Off-label prescription can be defined as the prescription of a drug for conditions other than current registered indications. This means that the drug is approved by either FDA or EMA for a certain disease, yet there is no definitive proof for the efficacy of the specific drug for other conditions. The physician’s decision to prescribe off-label in such cases is often based on the pathophysiology of the disease or shared symptoms with other diseases in which the biologic has proven to be effective. This is called rational prescription and may lead to innovative treatment options, especially in rare diseases.
- Types of inovative therapies
- Problems involved in innovative therapies
- Breakthrows
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 Innovative Therapies for Serious Diseases Conference Speakers
Recommended Sessions
- Advancements in Biotherapeutics
- Analytical Biotherapeutics
- Â Immunopharmacotherapy
- Â Innovative Therapies for Serious Diseases
- Bioanalytical Techniques
- Biotherapy
- Cancer Biotherapeutics
- Chromatographic Techniques
- Clinical Biotherapeutics
- Drug Analysis
- Drug Metabolism Studies
- MicroRNAs (miRNAs) Biotherapeutics
- Oncolytic Virotherapy
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- Regulatory Affairs and Drug Safety - PHARMACEUTICAL CHEMISTRY 2025 (France)
- Regulatory Affairs and Intellectual Property Rights - Future Pharma 2025 (Netherlands)
- Regulatory Affairs and Quality Assurance - Drug Delivery-2025 (Netherlands)
- Regulatory Authority Compliance - MedTech-2025 (Switzerland)
- Regulatory Harmonization & Compliance - Biologics Meet 2026 (UK)
- Regulatory Science and Clinical Trial Innovations - Euro Antibiotics 2025 (Netherlands)
- Regulatory Science and Translational Medicine - Drug Delivery-2025 (France)
- Rehabilitation and Physical Therapy in Pain - Pain Management 2026 (France)
- Risk-Based Monitoring and Trial Optimization - Clinical Trials-2026 (UK)
- Safety Reporting in Early Phase Trials - Clinical Trials-2026 (UK)
- Semi-Solid Dosage Forms - Formulations 2025 (France)
- Sexually Transmitted Bacterial Infections and Resistance Trends - Euro Antibiotics 2025 (Netherlands)
- Signal Prioritization and Management Techniques - Clinical Trials-2026 (UK)
- Single-Use Technologies in Production - Biologics Meet 2026 (UK)
- Smart Drug Delivery Systems - PHARMACEUTICA 2025 (Germany)
- Smart Drug Delivery Systems - Formulations 2025 (France)
- Smart Polymers and Biomaterials - Drug Delivery-2025 (Netherlands)
- Smart Polymers and Responsive Drug Carriers - Drug Delivery-2025 (France)
- Solid Dosage Forms - Formulations 2025 (France)
- Stewardship Programs in Human and Animal Health - Euro Antibiotics 2025 (Netherlands)
- Structure-Based Drug Design and Molecular Docking - Euro MedChem and CADD 2025 (France)
- Supply Chain Management - Pharmaceuticals-2025 (France)
- Sustainable Antibiotic Practices and Global Policy - Euro Antibiotics 2025 (Netherlands)
- Sustainable Biologics Manufacturing - Biologics Meet 2026 (UK)
- Synthetic and Bioorganic Chemistry - PHARMACEUTICAL CHEMISTRY 2025 (France)
- Synthetic and Green Medicinal Chemistry - Euro MedChem and CADD 2025 (France)
- Systems Pharmacology and Drug Modeling - Euro Pharmacology 2025 (France)
- Target Identification and Validation - Euro MedChem and CADD 2025 (France)
- Targeted Drug Delivery and Nanomedicine in Infectious Diseases - Euro Antibiotics 2025 (Netherlands)
- Targeted Drug Delivery and Precision Medicine - Drug Delivery-2025 (France)
- Targeted Therapies - Personalizedmedicine-2025 (Switzerland)
- Technology in Pharma Sciences - MedTech-2025 (Switzerland)
- Telemedicine - Personalizedmedicine-2025 (Switzerland)
- The Future of Pharma R&D - Future Pharma 2025 (Netherlands)
- The Role of CROs in Clinical Trial Execution - Clinical Trials-2026 (UK)
- Toxicological Impacts of Air and Water Pollution - Euro Pharmacology 2025 (France)
- Toxicology and Safety Pharmacology - Pharmacology-2025 (Spain)
- Toxicology: Mechanisms and Risk Assessment - Euro Pharmacology 2025 (France)
- Transdermal and Intradermal Delivery Systems - Drug Delivery-2025 (Netherlands)
- Translational Research - Personalizedmedicine-2025 (Switzerland)
- Trending: Digital Health and Telemedicine for Rare Care - ORPHAN DRUGS 2025 (France)
- Types of Formulations - Formulations 2025 (France)
- Vaccine Delivery Technologies - Drug Delivery-2025 (Netherlands)
- Vaccine Development Against Bacterial Pathogens - Euro Antibiotics 2025 (Netherlands)
- Vaccine Drug Delivery Systems - PHARMACEUTICA 2025 (Germany)
- Vaccines & Immunotherapy - Pharma Expo-2026 (Thailand)
- Veterinary Pharmacology - Pharmacology-2025 (Spain)
- Women in Rare Disease Leadership and Science - ORPHAN DRUGS 2025 (France)